General Cell Based Assays
Eurofins Discoverx PathHunter eXpress GPR137 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0361E2ACP1M)
The PathHunter GPR137 (TM7SF1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR137 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR137 and EA-tagged β-Arrestin-2. Activation of GPR137 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Senescence Detection Kit
Senescence Detection Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Adipolysis Assay Kit.
Adipolysis Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress UTR2 Total GPCR Internalization Assay, 10-Plate Kit. (93-0746E3CP5L)
The PathHunter UTR2 Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of UTR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged UTR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the UTR2 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical NFAT AcTVatIon InHBTr III 50mg
A cell-permeant inhibitor of NFAT signaling; binds calcineurin (Kd = 0.8 µM), preventing it from dephosphorylating NFAT
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, Control Lysate
HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, Control Lysate
Eurofins Discoverx PathHunter MRGPRX2 Bioassay Kit, 10-Plate. (93-0309Y2-00144)
The PathHunter MRGPRX2 Bioassay kit provides a robust, highly sensitive, and easy-to-use functional cell based assay to measure drug potency and detect neutralizing antibodies. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility, and faster implementation from characterization to lot release. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Cayman Chemical UrIc AcIdodIum salt 2mg
An end product of purine metabolism in humans that is mainly excreted in urine and can act as a potent peroxynitrite scavenger and antioxidant; high levels of serum uric acid (>120 UG/ml) are associated with gout, kidney stones, metabolic syndrome, hypertension, renal disease, and cardiovascular disease
Meso Scale Discovery R-PLEX Human IL-32 ASY
The R-PLEX Human IL-32 Assay Kit from Meso Scale Discovery measures IL-32 in human serum plasma and cell culture supernatants using electrochemiluminescence detection It offers high sensitivity a 5-log dynamic range and low sample volume needs The kit includes a 96-well plate with IL-32 capture antibodies detection antibodies buffers diluent and calibrators The assay takes about 3 5 hours and requires a MESO QuickPlex SQ 120 instrument It enables accurate quantitation of IL-32 an inflammatory cytokine in immune responses
Eurofins Discoverx PathHunter Human PRLHR β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human PRLHR β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PRLHR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human MIP-1 alpha (CCR1) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human MIP-1 alpha (CCR1) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse LTB4R β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse LTB4R β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mLTB4R1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Amsbio LLC Heparanase Assay Kit with Positive Control Enzyme
Heparanase Assay Kit with Enzyme as Positive Control
Revvity Health Sciences Inc HTRF Human Pro-Collagen Type 1 Detection Kit, 10,000 Assay Points
HTRF Human Pro-Collagen Type 1 Detection Kit, 10,000 Assay Points
Abcam Maleimide Quantification Assay Kit (Colorimetric).
Maleimide Quantification Assay Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement